Germany
BiDirect Study
Study website: www.campus.uni-muenster.de/index.php?id=2808&L=0
Organization website: www.campus.uni-muenster.de
Study population size: 2200 participants
Study population: healthy participants / patients with cardiovascular disease / patients with depression, aged 35-65 years old
Imaging modality 1: ultrasound – Carotid ultrasound
Imaging modality 2: MRI – Brain MRI
Key publications: not yet available.
CAPS
Carotid Atherosclerosis Progression Study
Study website: n.a.
Organization website: www.kgu.de
Study population size: 6982 participants
Study population: healthy population, aged 19 – 90 years old
Imaging modality 1: ultrasound – Carotid ultrasound
Key publications:
- Sitzer M, Skutta M et al, Modifiable Stroke Risk Factors in Volunteers Willing to Participate in a Prevention Program. Neuroepidemiology, 1998.
- Jerrard-Dunne P, Sitzer M, et al. Interleukin-6 promoter polymorphism modulates the effects of heavy alcohol consumption on early carotid artery atherosclerosis: the Carotid Atherosclerosis Progression Study (CAPS). Stroke, 2003.
- Lorenz MW, von Kegler S, et al. Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke, 2006.
- Bevan S, Lorenz MW, et al. Genetic variation in the leukotriene pathway and carotid intima-media thickness: a 2-stage replication study. Stroke, 2009.
- Lorenz MW, Schaefer C, et al. Is carotid intima media thickness useful for individual prediction of cardiovascular risk? Ten-year results from the Carotid Atherosclerosis Progression Study (CAPS). Eur Heart J, 2010.
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Lung Cancer Screening Intervention Trial
For the Early Detection of Lung Cancer
Study website: n.a.
Organization website: www.dkfz.de
Study population size: 4000 participants
Study population: healthy population – smokers, aged 50 – 69 years old
Imaging modality 1: MDCT – MDCT of the chest
Key publications: not yet available.
Rhineland Study
Deutsches Zentrum fur Neurodegenerative Erkrankungen
Study website: www.dzne.de/en/home.html
Organization website: www.dzne.de
Study population size: 30000 participants
Study population: healthy population
Imaging modality 1: MRI – brain
SHIP
Study of Health in Pomerania
Study website: www.medizin.uni-greifswald.de/cm/fv/english/ship_en.html
Organization website: www.medizin.uni-greifswald.de
Study population size: 9308 participants
Study population: healthy population, aged 20 – 79 years old
Imaging modality 1: ultrasound – Echocardiography, Ultrasound of liver, Carotid ultrasound, Ultrasound of thyroid gland
Imaging modality 2: MRI – Whole-body MRI
Key publications:
- Völzke H, Alte D, et al. Cohort Profile: The Study of Health in Pomerania. Int J Epidemiol, 2010.
- Hegenscheid K, Kühn JP, et al. Whole-body magnetic resonance imaging of healthy volunteers: pilot study results from the population-based SHIP study. Rofo, 2009.
- Hegenscheid K, Seipel R, et al. Potentially relevant incidental findings on research whole-body MRI in the general adult population: frequencies and management. Eur Radiol, 2012.
- Völzke H, Ittermann T, et al. Five-year change in morphological and functional alterations of the thyroid gland: the Study of Health in Pomerania. Thyroid, 2012.
The German National Cohort
Study website: www.nationale-kohorte.de/index_en.html
Organization website: www.lmu.de
Study population size: 20000 participants (planned, study start: 2011)
Study population: healthy population, aged 20 – 70 years old
Imaging modality 1: DEXA
Imaging modality 2: MRI – Whole-body MRI
Key publications:
- Bamberg F, KauczorD, et al. Whole-Body MR Imaging in the German National Cohort: Rationale, Design, and Technical Background. Radiology, 2015.