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Population Imaging » Germany

Germany

BiDirect Study

Study website: www.campus.uni-muenster.de/index.php?id=2808&L=0
Organization website: www.campus.uni-muenster.de
Study population size: 2200 participants
Study population: healthy participants / patients with cardiovascular disease / patients with depression, aged 35-65 years old
Imaging modality 1: ultrasound –  Carotid ultrasound
Imaging modality 2: MRI – Brain MRI

Key publications: not yet available.

 

CAPS

Carotid Atherosclerosis Progression Study

Study website: n.a.
Organization website: www.kgu.de
Study population size: 6982 participants
Study population: healthy population, aged 19 – 90 years old
Imaging modality 1: ultrasound –  Carotid ultrasound

Key publications:

  • Sitzer M, Skutta M et al, Modifiable Stroke Risk Factors in Volunteers Willing to Participate in a Prevention Program. Neuroepidemiology, 1998.
  • Jerrard-Dunne P, Sitzer M, et al. Interleukin-6 promoter polymorphism modulates the effects of heavy alcohol consumption on early carotid artery atherosclerosis: the Carotid Atherosclerosis Progression Study (CAPS). Stroke, 2003.
  • Lorenz MW, von Kegler S, et al. Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke, 2006.
  • Bevan S, Lorenz MW, et al. Genetic variation in the leukotriene pathway and carotid intima-media thickness: a 2-stage replication study. Stroke, 2009.
  • Lorenz MW, Schaefer C, et al. Is carotid intima media thickness useful for individual prediction of cardiovascular risk? Ten-year results from the Carotid Atherosclerosis Progression Study (CAPS). Eur Heart J, 2010.

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Lung Cancer Screening Intervention Trial

For the Early Detection of Lung Cancer

Study website: n.a.
Organization website: www.dkfz.de
Study population size: 4000 participants
Study population: healthy population – smokers, aged 50 – 69 years old
Imaging modality 1: MDCT –  MDCT of the chest

Key publications: not yet available.

 

Rhineland Study

Deutsches Zentrum fur Neurodegenerative Erkrankungen

Study website: www.dzne.de/en/home.html
Organization website: www.dzne.de
Study population size: 30000 participants
Study population: healthy population
Imaging modality 1: MRI – brain

 

SHIP

Study of Health in Pomerania

Study website: www.medizin.uni-greifswald.de/cm/fv/english/ship_en.html
Organization website: www.medizin.uni-greifswald.de
Study population size: 9308 participants
Study population: healthy population, aged 20 – 79 years old
Imaging modality 1: ultrasound –  Echocardiography, Ultrasound of liver, Carotid ultrasound, Ultrasound of thyroid gland
Imaging modality 2: MRI – Whole-body MRI

Key publications:

  • Völzke H, Alte D, et al. Cohort Profile: The Study of Health in Pomerania. Int J Epidemiol, 2010.
  • Hegenscheid K, Kühn JP, et al. Whole-body magnetic resonance imaging of healthy volunteers: pilot study results from the population-based SHIP study. Rofo, 2009.
  • Hegenscheid K, Seipel R, et al. Potentially relevant incidental findings on research whole-body MRI in the general adult population: frequencies and management. Eur Radiol, 2012.
  • Völzke H, Ittermann T, et al. Five-year change in morphological and functional alterations of the thyroid gland: the Study of Health in Pomerania. Thyroid, 2012.

 

The German National Cohort

Study website: www.nationale-kohorte.de/index_en.html
Organization website: www.lmu.de
Study population size: 20000 participants (planned, study start: 2011)
Study population: healthy population, aged 20 – 70 years old
Imaging modality 1: DEXA
Imaging modality 2: MRI – Whole-body MRI

Key publications:

  • Bamberg F, KauczorD, et al. Whole-Body MR Imaging in the German National Cohort: Rationale, Design, and Technical Background. Radiology, 2015.